Recent Advances in Through Vial Impedance Spectroscopy (TVIS) for Process Parameter Determination. 9th International ISL-FD Conference April 26-28 Havana, Cuba

Smith, G. (2017). Recent Advances in Through Vial Impedance Spectroscopy (TVIS) for Process Parameter Determination. Podium presentation at 9th International ISL-FD Conference April 26-28 Havana, Cuba

Outline of the presentation:

The presentation starts with an introduction to through vial impedance spectroscopy and a description of the measurement system before going on to describe various TVIS applications in the following stages of the process:

1. Freezing (Ice formation and phase separation)

2. Re-heating of the frozen mass to obtain a surrogate temperature calibration based on the TVIS parameter F_PEAK

3. Primary drying (Drying rate based on the TVIS parameter C"_PEAK from which the product dry layer resistance and evidence of micro-collapse are determined).