Smith, Geoffrey Recent Advances in Through Vial Impedance Spectroscopy (TVIS) for Process Parameter Determination. 9th International ISL-FD Conference April 26-28 Havana, Cuba Cite as :<div>Smith, G. (2017). Recent Advances in Through Vial Impedance Spectroscopy (TVIS) for Process Parameter Determination. Podium presentation at 9th International ISL-FD Conference April 26-28 Havana, Cuba<br></div><div><br></div><div>Outline of the presentation:</div><div>The presentation starts with an introduction to through vial impedance spectroscopy and a description of the measurement system before going on to describe various TVIS applications in the following stages of the process:</div><div>1. Freezing (Ice formation and phase separation)</div><div>2. Re-heating of the frozen mass to obtain a surrogate temperature calibration based on the TVIS parameter F<sub>PEAK</sub></div><div>3. Primary drying (Drying rate based on the TVIS parameter C"<sub>PEAK</sub> from which the product dry layer resistance and evidence of micro-collapse are determined).</div> lyophilization;TVIS;through-vial impedance spectroscopy;Pharmaceutical Sciences 2020-04-29
    https://figshare.dmu.ac.uk/articles/presentation/Recent_Advances_in_Through_Vial_Impedance_Spectroscopy_TVIS_for_Process_Parameter_Determination_9th_International_ISL-FD_Conference_April_26-28_Havana_Cuba/11988498
10.21253/DMU.11988498.v1